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HEPATITIS-B LINKS

HEP-B VACCINE: A HEALTH HAZARD

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HEP-B VACCINE LINKED TO DIABETES

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VACCINES:    HEPATITIS-B
HEP-B VACCINE LINK TO VARIOUS PATHOLOGIES

Below is a "Short" List of Medical Journal Articles Linking Hepatitis B Vaccine To Various Pathologies

Allen MB, Cockwell P, Page RL -
"Pulmonary and cutaneous vasculitis following hepatitis B vaccination"

Thorax 48(5):580-1 (1993)

Aubin F, Angonin R, Humbert P, Agache P -
"Lichen planus following hepatitis B vaccination"
Arch Dermatol 130(10):1329-30 (1994)

Authier FJ, Cherin P, Creange A, Bonnotte B, Ferrer X, Abdelmoumni A, Ranoux D, Pelletier J, Figarella-Branger D, Granel B, Maisonobe T, Coquet M, Degos JD, Gherardi RK -
"Central nervous system disease in patients with macrophagic myofasciitis"
Brain 124(Pt 5):974-83 (2001)  
Central nervous system disease in patients with macrophagic myofasciitis - Pubmed ID - 11335699
See full text article: Central nervous system disease in patients with macrophagic myofasciitis

Bensaid J, Denis F -
"Benign acute pericarditis after vaccination against hepatitis B"
Presse Med 22(6):269 (1993)

Berkman N, Benzarti T, Dhaoui R, Mouly P -
"Bilateral neuro-papillitis after hepatitis B vaccination"
Presse Med 25(28):1301 (1996)

Berkman N -
"A case of segmentary unilateral occlusion of the central retinal vein following hepatitis B vaccination"
Presse Med 26(14):670 (1997)

Bourges JL, Pisella PJ, Laurens C, Limon S -
"Multifocal placoid epitheliopathy and anti-hepatitis B vaccination"
J Fr Ophtalmol 21(9):696-700 (1998)
"The appearance of ocular pathological outcomes following an hepatitis B vaccination is uncommon. Among them, acute multiple posterior placoid pigment epitheliopathy has been noticed after injections of Engerix B recombinant vaccine. We describe the case of an 11-year-old child who presented this affection following a Genhevac B recombinant vaccine injection."

Bracci M, Zoppini A -
"Polyarthritis associated with hepatitis B vaccination"
Br J Rheumatol 36(2):300-1 (1997)

Casals JL, Vazguez MA -
"Arthritis induced by antihepatitis B vaccine"
An Med Interna 16(11):601-2 (1999)

Christau B, Helin P -
"Reactive arthritis following vaccination against hepatitis B"
Ugeskr Laeger 149(28):1882 (1987)

Creange A, Temam G, Lefaucheur JP -
"Lumbosacral acute demyelinating polyneuropathy following hepatitis B vaccination"
Autoimmunity 30(3):143-6 (1999)
We report a patient who presented with an acute inflammatory demyelinating polyneuropathy, that followed the second injection of a hepatitis B vaccination, and characterized by motor and sensory deficit restricted to lower limbs and perineum, and persistent bladder dysfunction. The relationship between the preceding event and neurological disease is discussed.

Daoud MS, Dicken CH -
"Anetoderma after hepatitis B immunization in two siblings"
J Am Acad Dermatol 36(5 Pt 1):779-80 (1997)

Devin F, Roques G, Disdier P, Rodor F, Weiller PJ -
"Occlusion of central retinal vein after hepatitis B vaccination"
Lancet 347(9015):1626 (1996

Di Giusto CA, Bernhard JD -
"Erythema nodosum provoked by hepatitis B vaccine"
Lancet 2(8514):1042 (1986)

Fernandez-Funez A, Polo Romero FJ -
"Juvenile dermatomyositis concomitant with hepatitis B vaccination"
Med Clin (Barc) 111(17):675 (1998)

Fraser PA, Wilson JD -
"Reiter's syndrome attributed to hepatitis B immunisation"
BMJ 309(6967):1513 (1994)

Fried M, Conen D, Conzelmann M, Steinemann E -
"Uveitis after hepatitis B vaccination"
Lancet 2(8559):631-2 (1987)

"Ganry O, Lerailler F, Vercelletto M, Chiffoleau A, Larousse C -
"Peripheral facial paralysis following vaccination against hepatitis B. Apropos of a case"
Therapie 47(5):437-8 (1992)

Germanaud J, Causse X, Trinh DH, Pfau-Fandard B, Trepo C -
"A case of severe cytolysis after hepatitis B vaccination"
Am J Med 98(6):595-6 (1995)

Gherardi RK, Coquet M, Cherin P, Belec L, Moretto P, Dreyfus PA, Pellissier JF, Chariot P, Authier FJ -
"Macrophagic myofasciitis lesions assess long-term persistence of vaccine-derived aluminium hydroxide in muscle"
Brain 124(Pt 9):1821-1831 (2001)
PunMed - 11522584
See Full Text Article: http://brain.oxfordjournals.org/cgi/content/full/124/9/1821

Gisserot O, Carsuzaa F, Marlier S, Morand JJ, Marrot E -
"Lichen planus after hepatitis B vaccination. 3 new cases"
Presse Med 26(16):760 (1997)

Grasland A, Le Maitre F, Pouchot J, Hazera P, Bazin C, Vinceneux P -
"Adult-onset Still's disease after hepatitis A and B vaccination"
Rev Med Interne 19(2):134-6 (1998)
"The authors report a case of adult Still's disease apparently triggered by hepatitis A and B vaccination. The patient was a 38-year-old woman who presented with fever, hepatitis, pneumonitis and neurologic symptoms, compatible with the diagnosis of adult Still's disease..."

Heinzlef O, Moguilewski A, Roullet E -
"Acute aseptic meningitis after hepatitis B vaccination"

Presse Med 26(7):328 (1997)

Hutteroth TH, Quast U -
"Aluminum hydroxide granuloma following hepatitis B vaccination"
Dtsch Med Wochenschr 115(12):476 (1990)

Islek I, Cengiz K, Cakir M, Kucukoduk S -
"Nephrotic syndrome following hepatitis B vaccination"
Pediatr Nephrol 14(1):89-90 (2000)

Kaplanski G, Retornaz F, Durand J, Soubeyrand J -
"Central nervous system demyelination after vaccination against hepatitis B and HLA haplotype"
J Neurol Neurosurg Psychiatry 58(6):758-9 (1995)

Lasheras Carbajo MD, Palacios Diez M, Gonzalez Diego P, Martin Scapa MA, Cano Ruiz A, Asensio Vegas A -
"A case of intense cytolysis following the administration of a hepatitis B vaccine"
Rev Clin Esp 199(1):49-50 (1999)

Lear JT, English JS -
"Anaphylaxis after hepatitis B vaccination"
Lancet 345(8959):1249 (1995)

Le Goff P, Fauquert P, Youinou P, Hoang S -
"Periarteritis nodosa following vaccination against hepatitis B"
Presse Med 17(34):1763 (1988)

Le Hello C, Cohen P, Bousser MG, Letellier P, Guillevin L -
"Suspected hepatitis B vaccination related vasculitis"
J Rheumatol 26(1):191-4 (1999)
"We describe 3 cases of vasculitis occurring after such immunization that are thought to have been vaccine induced. Vasculitides are now recognized as possible severe adverse side effects of immunization.

Maillefert JF, Sibilia J, Toussirot E, Vignon E, Eschard JP, Lorcerie B, Juvin R, Parchin-Geneste N, Piroth C, Wendling D, Kuntz JL, Tavernier C, Gaudin P -
"Rheumatic disorders developed after hepatitis B vaccination"
Rheumatology (Oxford) 38(10):978-83 (1999)
OBJECTIVE: To obtain an overview of rheumatic disorders occurring after hepatitis B vaccination. METHODS: A questionnaire was sent to rheumatology departments in nine French hospitals. Criteria for entry were rheumatic complaints of 1 week's duration or more, occurrence during the 2 months following hepatitis B vaccination, no previously diagnosed rheumatic disease and no other explanation for the complaints.
RESULTS: Twenty-two patients were included. The observed disorders were as follows: rheumatoid arthritis for six patients; exacerbation of a previously non-diagnosed systemic lupus erythematosus for two; post-vaccinal arthritis for five; polyarthralgia-myalgia for four; suspected or biopsy-proved vasculitis for three; miscellaneous for two.
CONCLUSIONS: Hepatitis B vaccine might be followed by various rheumatic conditions and might trigger the onset of underlying inflammatory or autoimmune rheumatic diseases. However, a causal relationship between hepatitis B vaccination and the observed rheumatic manifestations cannot be easily established. Further epidemiological studies are needed to establish whether hepatitis B vaccination is associated or not with an incidence of rheumatic disorders higher than normal.

Mamoux V, Dumont C -
"Lupus erythematosus disseminatus and vaccination against hepatitis B virus"
Arch Pediatr 1(3):307-8 (1994)

Marsaudon E, Barrault MF -
"Meningeal reaction after vaccination against hepatitis B"
Presse Med 25(32):1561-2 (1996)

Martinez E, Domingo P Kaltenbach G, Lujic J, Arpin-Bott MP, Imler M -
"Adult onset Still disease and subacute thyroiditis"
Rev Med Interne 17(5):427 (1996)

Martinez E, Domingo P -
"Evans's syndrome triggered by recombinant hepatitis B vaccine"
Clin Infect Dis 15(6):1051 (1992)

Masse I, Descoffres MC -
"Hypersensitivity vasculitis after hepatitis B vaccination"
Presse Med 27(20):965-6 (1998)

Mathieu E, Fain O, Krivitzky A -
"Cryoglobulinemia after hepatitis B vaccination"
N Engl J Med 335(5):355 (1996)

Nagafuchi S, Tokiyama K, Kashiwagi S, Yayashi S, Imayama S, Niho Y -
"Eosinophilia after intradermal hepatitis B vaccination"
Lancet 342(8877):998 (1993)

Orlando MP, Masieri S, Pascarella MA, Ciofalo A, Filiaci F -
"Sudden hearing loss in childhood consequent to hepatitis B vaccination: a case report"
Ann N Y Acad Sci 830:319-21 (1997)

Peyriere H, Hillaire-Buys D, Pons M, Navarre C, Davy JM, Blayac JP -
"Acute pericarditis after vaccination against hepatitis B: a rare effect to be known"
Rev Med Interne 18(8):675-6 (1997)

Poulton JK, Kauffman CL, Lutz LL, Sina B -
"Solitary mastocytoma arising at a hepatitis B vaccination site"
Cutis 63(1):37-40 (1999)

Rabaud C, Barbaud A, Trechot P -
"First case of erythermalgia related to hepatitis B vaccination"
J Rheumatol 26(1):233-4 (1999)

Reutens DC, Dunne JW, Leather H -
"Neuralgic amyotrophy following recombinant DNA hepatitis B vaccination"
Muscle Nerve 13(5):461 (1990)

Sebag O, Bolla G, Bebin B, Sebag F-
"Exacerbation of chronic juvenile arthritis induced by hepatitis B vaccination"
Arch Pediatr 5(9):1046 (1998)

Skowron F, Grezard P, Berard F, Balme B, Perrot H -
"Persistent nodules at sites of hepatitis B vaccination due to aluminium sensitization"
Contact Dermatitis 39(3):135-6 (1998)

Song HK, Kim HC, Yun YH -
"Acute Myelitis after hepatitis B vaccination"
J Korean Med Sci 12(3):249-51 (1997)
"We report a case of myelitis after plasma-derived hepatitis B vaccination. The patient was a 31-year-old man who presented with progressive sensory symptoms in extremities that developed 2 weeks after a third vaccination. MRI of the cervicothoracic region revealed swelling and T2 high signal at the level of C4 to C5 cord, and isolated enhancement in the posterior columns between C4 and C5 cord..."

Toft J, Larsen S, Toft H -
"Subacute thyroiditis after hepatitis B vaccination"
Endocr J 45(1):135 (1998)

Tourbah A, Gout O, Liblau R, Lyon-Caen O, Bougniot C, Iba-Zizen MT, Cabanis EA -
"Encephalitis after hepatitis B vaccination: recurrent disseminated encephalitis or MS?"
Neurology 53(2):396-401 (1999)
OBJECTIVE: To describe clinical and MRI features of patients with a disease suggestive of CNS inflammation after hepatitis B vaccination.
METHODS: Eight patients with confirmed CNS inflammation occurring less than 10 weeks after hepatitis B vaccination are described. They received follow-up clinically and on MRI for a mean period of 18 months.
RESULTS: Clinical and MRI findings were compatible with acute disseminated encephalomyelitis. However, clinical follow-up, repeated MRI, or both showed the persistence of inflammatory activity, which makes this encephalitis more suggestive of MS than of acute disseminated encephalomyelitis.
CONCLUSION: The persistent inflammatory activity observed clinically and on MRI in these patients is comparable with that usually observed in MS. Epidemiologic studies are currently testing the hypothesis of a triggering role of hepatitis B vaccination in CNS demyelination.

Treves R, Lacoste L, Bontoux D, Pitrou E, Bertin P, Bonnet C -
"Erosive nodular rheumatoid arthritis triggered by hepatitis B vaccination"
Presse Med 26(14):670 (1997)

Trevisani F, Gattinara GC, Caraceni P, Bernardi M, Albertoni F, D'Alessandro R, Elia L, Gasbarrini G -
"Transverse myelitis following hepatitis B vaccination"
J Hepatol (2):317-8 (1993)

Vanoli M, Gambini D, Scorza R -
"A case of Churg-Strauss vasculitis after hepatitis B vaccination"
Ann Rheum Dis 57(4):256-7 (1998)

Vautier G, Carty JE -
"Acute sero-positive rheumatoid arthritis occurring after hepatitis vaccination"
Br J Rheumatol 33(10):991 (1994)


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